XBP-1 Description
BSA blocked X-box binding protein 1 (XBP-1) is a basic-region, leucine zipper type transcription factor that belongs to the CREB/ATF family and mediates one of the three arms of unfolded protein response (UPR) adaptation to endoplasmic reticulum (ER) stressors. The accumulation of unfolded or misfolded proteins in the ER is a threat to cell survival and results in a condition known as ER-stress.1,2 To overe this...